LRS Chambers (Leukoreduction System Chambers) uses saturated, fluidized, particle bed filtration technology to enrich white blood cells (WBCs). This is an efficient, valid, and economic source of functional monocyte-derived dendritic cells and lymphocytes.
The LRS Chamber is a relatively new technology, but it has quickly become a popular choice for enriching WBCs. It is more efficient and cost-effective than traditional methods, such as density gradient centrifugation. Additionally, LRS Chambers produces a higher quality product, with more viable and functional WBCs. The LRS Chamber is a valuable tool for any laboratory that needs to enrich WBCs for research or clinical applications.
LRS Chambers work by passing blood through a column of fluidized particles. The particles are coated with antibodies that bind to WBCs. As the blood passes through the column, the WBCs are captured on the particles. The remaining blood components, such as red blood cells and plasma, are then passed through a filter to remove any remaining WBCs. The LRS Chamber can be used to enrich WBCs from whole blood, apheresis products, or cord blood.
Product Use Examples
The enriched WBCs can then be used for a variety of research and clinical applications, including: immunology research, cellular therapy and vaccine development.