Starting with highly qualified, reliable donors we manufacture cells characterized to your requirements, reducing variabilities in clinical responses, and increasing your probability of success in your trial. Trust Excellos to support your programs in adoptive cell therapies including: TIL Therapy (Tumor Infiltrating Lymphocytes), Autologous and Allogeneic CAR T/NK Therapies, and TCR Therapy.
Go beyond typical cell and donor screening with the Excellos 360 platform to get a comprehensive immune profile for each donor with an assessment of the metabolic and effector potential of their cells.
Get custom sourced, diverse starting material that meets the needs of your program. We source from a consented, recallable donor pool, with rich diversity (ethnicity, sex, age).
With cGMP production in ISO 7 cleanrooms, your custom donor cells are processed, transduced, harvested, expanded and cryopreserved. Upon your demand, cryopreserved cells undergo large-scale expansion and when densities have been achieved are harvested, analyzed for safety, cryopreserved and then shipped to you.
Built on the foundation of the San Diego Blood Bank, and with over 70 years of experience in blood and tissue collection and handling, Excellos started in 2015 and is your select partner. With our comprehensive quality assurance and phase-appropriate regulatory compliance support, you get the support you need.
Excellos is backed by the San Diego Blood Bank (established in 1950). Our founder team not only used to work for the blood bank, we continue to have a strong lab presence on-site at the San Diego Blood Bank.
Excellos works under a comprehensive quality assurance umbrella including Quality by Design (QBD) and Manufacturing by Design (MBD). Excellos also has numerous accreditations and licensures. See more here.
With Excellos products you get excellent characterization information that can include: BMI, age, longitudinal data, HLA type, and telomere scores. Because many of our donors are high retention, you can also perform longitudinal research that is specific to your parameters.
As your partner, we can flex terms to meet your needs including fee-for-service, royalty sharing, and milestones. The science may be difficult, but our terms aren’t.
Whether you are in the discovery, clinical or commercial stage, Excellos has a solution for you. We have extensive products and services tailored to your needs.
We provide a continuum of services from donor recruitment to establishment of genetically modified working cell banks. These can include: apheresis donor cell collection, cell processing, cell isolation and enrichment, genetic modification, analysis, expansion, and cryopreservation
Excellos is a spin-out of the San Diego Blood Bank. Many of our employees worked at the San Diego Blood Bank and we still maintain laboratory space in the bank.
Excellos 360 is a proprietary mechanism that creates a comprehensive immune cell profile and an assessment of the metabolic and effector potential for each donor sample. By going beyond surface cell markers, Excellos 360 can help improve clinical outcomes and reduce costs of manufacturing.
The best time to engage Excellos is in Pre-clinical and Phase 1. We work with your API to manufacture your producer line. To take full advantage of Excellos 360, it is best to start during donor collection.